A bunch of quick health & biology finds #1
lauric acid (from coconut oil) + glucose reverses heart atrophy
https://onlinelibrary.wiley.com/doi/full/10.1111/cas.14656
Combined administration of lauric acid and glucose improved cancer-derived cardiac atrophy in a mouse cachexia model.
(paradoxically a study from the same group shows no functional harm from the same 2% in diet, but at 5% the balance tips over and damage appears with reduced heart weight (atrophy) because of excess oxidative stress, possibly due to overstimulating mitochondria https://pmc.ncbi.nlm.nih.gov/articles/PMC6240279/, when looking at their actual lauric acid intake, which is 50% of coconut oil, it was a bit under double what the 2% diet group ate)
~20g - 30g coconut oil daily should be a good amount for benefits without tipping over to causing oxidative stress and instead helping lower it, especially if split twice into meals
https://pubmed.ncbi.nlm.nih.gov/37409587/
Its also good for improving chances of being able to breastfeed
bromelain increases tendon healing at ~70mg - 100mg (increases tenocyte proliferation / maturation) https://www.liebertpub.com/doi/abs/10.1089/jmf.2010.0078
in rare cases milk sugar (lactose->galactose) causes cataracts https://www.sciencedirect.com/science/article/abs/pii/0002939452915870
and can inhibit proliferation of the thymus / increase its destruction.
Hesperidin found in orange juice, Or Curcumin, are fully protective measured in some areas https://pmc.ncbi.nlm.nih.gov/articles/PMC7520561/#sec15
https://www.researchgate.net/figure/Effects-of-curcumin-on-cells-proliferation-of-the-thymus-were-examined-by-IHC-method-3h_fig5_343073220
(I prefer the 1st, would avoid curcumin formulations designed to go higher in the brain, and especially avoid the ones that come with piperine as this might be serotonergic and lower thyroid hormone)
100mg nicotinamide / niacinamide in humans as an acutely raises plasma serotonin >50% (and increases histamine) through using up methyl group pool for the histamine rise, and possibly through no longer needing tryptophan to create NAD+ (through the kynurenine pathway) allowing for more serotonin production https://www.researchgate.net/publication/235682105_Excess_nicotinamide_increases_plasma_serotonin_and_histamine_levels
(I also think this might be why people notice a sedative and “spaced out” effect on nicotinamide, possibly raising serotonin in the brain)
(If trying to get benefits, it might be best to split the doses, or use lower)
There's an antimicrobial peptide in saliva that inhibits viruses / covid (LL37) - but nicotinamide/niacinamide is needed for the full effect https://pmc.ncbi.nlm.nih.gov/articles/PMC10663372/
Saturating gauze with lactoferin closed wounds after bone necrosis surgery in 1-2 weeks instead of 2-3 months https://pubmed.ncbi.nlm.nih.gov/29435826/
Brain restoration timeframe for previous meth users (maybe similar with a lot of porn time or maybe overstimulating multiplayer games for hours routinely) - in abstinence setting , takes 8 weeks to reset depression+anxiety scores from 13.1 to 4.8 , a 65% reduction by 2 months with 3 days a week information program https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560957/
Or get a 85% depression+anxiety reduction by the 2 months if exercise (or possibly heating body?) 3 days a week 45 mins (30 minutes cardio, 15 minutes weights) + 5 min stretch
normalized REM sleep start = commonly 60+ minutes , in depression its common to see it hit at 0 minutes or <60
https://core.ac.uk/reader/148255294?utm_source=linkout
https://pubmed.ncbi.nlm.nih.gov/183839/7
